Book NowBook NowPolynucleotide therapy is an advanced biostimulatory treatment designed to restore the skin’s structure and resilience at a cellular level.
Polynucleotides (PNs) are naturally derived DNA fragments that boost fibroblast activity, collagen synthesis, and tissue regeneration.
This treatment is ideal for patients seeking natural rejuvenation and firmness without added volume.
It effectively treats:
Polynucleotide therapy improves skin texture and hydration, giving a firmer, smoother, more luminous complexion.
Polynucleotide therapy is an advanced biostimulatory treatment designed to restore the skin’s structure and resilience at a cellular level.
Polynucleotides (PNs) are naturally derived DNA fragments that boost fibroblast activity, collagen synthesis, and tissue regeneration.
This treatment is ideal for patients seeking natural rejuvenation and firmness without added volume.
It effectively treats:
Polynucleotide therapy improves skin texture and hydration, giving a firmer, smoother, more luminous complexion.
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At Harley Street MD, all polynucleotide treatments are performed by GMC-registered doctors using premium medical-grade biostimulators.
Our treatment process includes:
The therapy is fully customisable and suitable for all skin types, delivering regenerative benefits with minimal downtime.
Polynucleotides are naturally derived DNA fragments that stimulate cell regeneration, collagen production, and tissue repair. They improve skin elasticity, hydration, and overall texture without adding volume.
Once injected, polynucleotides activate fibroblasts in the skin, encouraging collagen and elastin synthesis. This rejuvenates the skin from within, making it firmer, smoother, and more radiant over time.
Common treatment areas include the face, neck, under-eye region, décolletage, and hands. It can also be used on delicate or sun-damaged skin that requires regeneration.
This treatment is suitable for anyone seeking natural skin tightening and revitalisation without fillers. It’s ideal for mild skin laxity, fine lines, or dull, dehydrated skin.
Polynucleotides work differently from hyaluronic acid-based boosters. Instead of just hydrating, they repair and regenerate skin cells for longer-lasting improvements in firmness and quality.
A course of three sessions spaced 3–4 weeks apart is typically recommended for optimal results, followed by maintenance every 6–9 months.
Results develop gradually, with visible improvement in tone and elasticity after 3–6 weeks as new collagen forms.
Discomfort is minimal. A topical numbing cream is applied before treatment to ensure comfort during the procedure.
Results typically last between 6–12 months depending on skin condition, lifestyle, and maintenance treatments.
Yes. Polynucleotides are biocompatible and clinically tested for safety. All procedures are performed by GMC-registered doctors in a CQC-registered clinic.
All treatments are performed by GMC-registered doctors only.
The clinic is accredited by JCCP and CPSA, and registered with the Care Quality Commission (CQC) for medical safety and patient care.
The CQC has rated Harley Street MD “Outstanding” in its inspections.
This ensures the highest level of safety, ethics, and professional care in non-surgical aesthetic medicine.
With over 17 years of experience, Dr Tan is a BCAM full member and advanced injector, specialising in natural, proportionate results using advanced techniques.
UK-trained medical doctor, practising aesthetics since 2008
Certified Advanced Injector by Allergan and MD Codes™ expert
Member of BCAM, MRCS(Ed), ECAMS, MRCGP, FHEA
Featured on TV and in media as an expert in cosmetic medicine
