Book NowBook NowTestosterone levels naturally decline with age, but some men experience a clinically significant deficiency known as hypogonadism. Because symptoms of low testosterone can overlap with stress, lifestyle factors, or other medical conditions, accurate screening and diagnosis are essential before any treatment is considered.
This screening package is designed to assess whether testosterone deficiency may be contributing to symptoms such as:
Through medical evaluation and laboratory testing, this assessment determines whether hormonal imbalance is present and whether TRT may be clinically indicated. Treatment is only offered where appropriate following full screening and diagnosis.
Testosterone levels naturally decline with age, but some men experience a clinically significant deficiency known as hypogonadism. Because symptoms of low testosterone can overlap with stress, lifestyle factors, or other medical conditions, accurate screening and diagnosis are essential before any treatment is considered.
This screening package is designed to assess whether testosterone deficiency may be contributing to symptoms such as:
Through medical evaluation and laboratory testing, this assessment determines whether hormonal imbalance is present and whether TRT may be clinically indicated. Treatment is only offered where appropriate following full screening and diagnosis.
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At Harley Street MD, testosterone replacement therapy is never initiated without comprehensive screening. All assessments and prescriptions are carried out by GMC-registered doctors specialising in endocrinology and men’s health.
This package focuses on medical evaluation, risk assessment, and clinical suitability, not automatic hormone prescribing. Our screening process includes:
Where appropriate, a personalised TRT plan may be recommended following screening, using injections, gels, or oral options. Additional optimisation therapies, such as peptides or growth hormone support, may be discussed only after suitability is confirmed.
Regular follow-ups and ongoing blood monitoring are required for any patient proceeding to treatment, ensuring long-term safety and effectiveness.
This screening package is designed to provide clarity, diagnosis, and medical guidance, allowing patients to make informed decisions based on evidence-based hormonal assessment rather than assumptions or cosmetic use.
Testes (Primary Site)
Adrenal Glands (Minor Contribution)
Yes. When you begin Testosterone Replacement Therapy (TRT), you introduce external (exogenous) testosterone into your body. Whether it’s delivered through injections, topical gels, or oral formula-tions, this added testosterone signals your body to decrease its own natural production.
Your brain cannot distinguish between natural (endogenous) testosterone and externally supplied (ex-ogenous) testosterone. Because both forms are biologically identical, your body interprets the total amount of circulating testosterone as sufficient. As a result, it reduces the signal sent to the testicles to produce more.
It’s important to understand that having lower natural testosterone during TRT does not mean you are deficient. In fact, it typically indicates that your total testosterone level is higher and more stable, helping alleviate symptoms associated with low testosterone. Your body is simply conserving energy and resources because it senses adequate hormone levels.
This reduction in natural production is normal, expected, and not harmful. What matters most is that your overall testosterone levels—with the help of TRT—are optimized to support your health and well-being.
Because Testosterone Replacement Therapy reduces the stimulation of the testicles, some individuals may experience a decrease in testicular size or volume. Semen quantity may also decline, and sperm count can be reduced when the testicles are not producing testosterone naturally.
If maintaining testicular size, semen volume, or fertility is important, we can often incorporate HCG (Human Chorionic Gonadotropin) alongside TRT. HCG helps stimulate the testicles and can support sperm production and testicular function. This approach is common and can be tailored based on your goals and medical needs.
Unfortunately, no. Once you introduce any amount of external (exogenous) testosterone, your natu-ral production will decrease. Because the body cannot distinguish between natural and external tes-tosterone, it will reduce its own output—even if the dose you take is small.
So rather than “topping up,” you are essentially creating a new, externally supported testosterone level.
Yes. In some cases, it is possible to stimulate the body’s own testosterone production rather than using external testosterone. This is typically done using medications such as hCG or selective oestro-gen receptor modulators (SERMs), depending on the clinical situation.
However, several factors must be considered:
1. Underlying cause Low testosterone can result from testicular, pituitary, or lifestyle-related factors. Natural stimulation is only effective if the body’s hormone pathway is capable of responding.
2. Effectiveness Response varies between individuals. Some men experience significant improvement, while others achieve only modest increases that may not relieve symptoms. For many, TRT provides more stable results. Exogenous testosterone can provide more consistent level than pure stimulation, which will be impacted by nutrition status, exercise routine, baseline level, age, testicular sizes and various other variables. That is because your body is making the testosterone as compared to being supplemented with ready-made testosterone.
3. Risk of desensitisation Long-term or high-dose stimulation (particularly with hCG only treatment) may reduce the testes’ responsiveness over time. For this reason, prolonged high-dose protocols are not recommended un-less specifically indicated.
4. Safety and monitoring Stimulation protocols require even more regular blood testing to monitor testosterone, oestradiol, and other markers. Side-effects must be carefully assessed.
5. Appropriate situations Natural testosterone stimulation may be considered for:
6. When TRT may be more suitable If stimulation does not adequately raise testosterone or improve symptoms, medically super-vised TRT may offer a safer and more predictable alternative.
A clinician will assess your symptoms, medical history, blood results, and long-term goals to determine whether natural stimulation or TRT is the most appropriate option.
Yes, there are treatment protocols designed to stimulate your body’s own testosterone production without replacing it with external testosterone. However, there are many key points needed to be taken into considerations such as safety, effectiveness, ease for administration and risks associated with it. Long term stimulation protocol is only recommended based on specific situation. We would always recommend options that are safer and more controllable first. By large, we do not advocate long term, high dose stimulation protocol, which is likely to cause desensitisation of your testosterone production.
These options can be discussed during your consultation to determine the best path based on your goals, symptoms, and overall health
Most men notice improvements in mood, energy, libido and mental clarity within 4–6 weeks. Muscle composition and fat loss changes typically occur over 3–6 months, enhanced with proper training and nutrition.
When medically supervised with proper monitoring, TRT is considered safe and effective. We routinely monitor heart health, prostate health and blood parameters to ensure optimal, evidence-based care.
Yes. We are one of the UK’s leading private clinics for men who use or have used anabolic steroids. We provide harm-reduction, cardiovascular screening, full hormonal panels, PCT planning, and safe transition to TRT when clinically indicated.
For men with low testosterone, TRT often improves libido, morning erections and sexual confidence. If erectile dysfunction persists, we also offer advanced ED treatments available at the clinic.
Restoring testosterone often enhances muscle protein synthesis, strength, recovery and meta-bolic rate. Many of our high-performing clients notice better gym progress, improved body composition and more stable energy levels.
Absolutely. Our clinic proudly supports all men, including gay, bisexual, transmasculine and non-binary clients. Care is personalised, discreet and non-judgmental.
We typically treat men aged 30–50, though treatment is based on symptoms, clinical need and diagnostic criteria—not age alone.
Testosterone alone may reduce sperm production. At our clinic, we use hCG protocols to preserve or restore fertility when required.
We follow international guidelines. Most men require blood tests at 6–12 weeks, then every 3–6 months. Those with complex needs or anabolic history may need closer supervision.
Moderate alcohol is acceptable, but heavy drinking can worsen hormonal balance. We provide lifestyle counselling to help optimise results.
Fatigue is a common symptom. We use advanced blood panels to rule out thyroid issues, vit-amin deficiencies, anaemia and sleep disorders—not just testosterone—ensuring accurate di-agnosis.
Current evidence shows TRT is safe when properly prescribed and monitored. At Harley Street Medical Doctors, we include cardiac risk screening and ongoing assessment to ensure safety.
Some men notice mild testicular shrinkage due to reduced natural production. hCG therapy can prevent or reverse this and is available at our clinic.
Men with clinically low testosterone often report improvements in mental wellbeing, confi-dence, motivation and cognitive performance once levels are restored.
TRT restores testosterone to normal, physiological levels. Steroid cycles push hormones into the supraphysiological range, increasing risks. We specialise in both, offering safe medical guidance to bodybuilders and fitness enthusiasts.
Yes. Most clients feel improved endurance, strength and recovery. Our doctors can advise on training, nutrition, peptides and longevity therapies to enhance results safely.
TRT is usually a long-term therapy. Many men remain on it indefinitely, similar to thyroid treatment. You can stop, but symptoms may return.
Yes, provided it is medically appropriate. Older men require more thorough cardiovascular and prostate screening, which we provide.
Many men report deeper, more restorative sleep once hormonal levels stabilise. Sleep optimisation is part of our holistic care.
Injectable testosterone generally provides more stable levels with fewer fluctuations. Gels are useful for certain patients. We guide you to the best, evidence-based choice.
Yes. For men coming off anabolic steroids, we offer structured PCT plans using evidence-based protocols and specialist hormonal monitoring.
Completely confidential. We work with high-profile patients, athletes, executives, and indi-viduals who require maximum privacy.
We conduct detailed bloodwork, medical history, physical examination and symptom assess-ment. Only patients who meet strict diagnostic criteria are offered treatment.
The initial TRT Screening Package is £800, including:
Ongoing treatment is tailored and competitively priced for the Harley Street area, reflecting specialist expertise.
You can call, email or book online. Our team will arrange your screening, answer any questions and support you through every step of your TRT journey.
